Genzyme Summary Essay Example for Free

Genzyme Summary Essay Genzyme was founded in 1981, Sanofi purchased the company in 2011. They went public in 1986, raising 27 million dollars. Genzyme startet as a start up Company by scientists studying genetically inherited enzyme diseases. Their strategy didn’t focus on the â€Å"blockbuster drugs† like other biotechnology companies but drugs for rare diseases. To developing a drug, it takes 10-14 years at the cost of around 800 million. But the blockbuster drugs had 1 billion dollars revenue. Genzyme has received several honor awards like â€Å"national medal of technology†. The food and drug administration established in 1983 the â€Å"Orphane drug act† giving seven years market exclusivity to developers of drugs for rare diseases. This gave Genzyme big advantage when it comes to clinical trials, advertising and sales, it does not requires a lot. Their first success was the â€Å"Ceredase† drug- to treat the Gaucher`s disease. It was sold to over 4000 patients, with annual revenue of 800 million dollars. They had different way of manufacturing and sales compare to other companies. They did not do licensing to large pharmaceutical company. Genzyme was the worlds third largest biotech company in 2006 only profiting of rare diseases. Reflection of the case * Avoided â€Å"blockbuster† market and good management Good strategic to focus on a niche market instead of the †blockbuster† market. The degree of existing rivalry and entry barriers was low. Henri Termeer took a risk in moving to a start up company but with his experience and expertise, the company went stronger and independent. * First ones to market and the exclusivity Genzyme entered a small, untapped market. Being the first biotech company that focus on rare diseases and having the market exclusivity made them leading biotech company. They had the ability to identify almost all customers. They had big advantage when is comes to clinical trials, restrictions, FDA and small numbers of test patients required.

Asian American Stereotypes in Film Essay -- essays research papers

Asian Americans only make up a small percent of the American population. Even more significant is that this percentage live mostly on the west and east coasts of mainland United States and Hawaii; leaving the rest of the American population to most likely get their exposures to Asians through television and movies. However the exposure they have receive throughout the history of cinematography has been hardly flattering. Throughout the course of history Asians in film have been portrayed as evil or the "yellow peril" as described by others. If Asians are not being classified as evil in this picture then they are most likely the comic relief, with their lack of coordination or grasp of the English language. With these common stereotypes in place, it gives a white American viewer a sense or need to destroy this Asian villain or superiority over the comedic character portrayed in the film. In the film Gung Ho filmed in the year 1986, the story is told of the plight of the people working in the region known as the Rust Belt. The group that is the focal point of this story is the relation between Asian men in an American town and the differences they share are played out in this movie. The stereotypes enlisted in this movie are both that of a villainous nature and a comedic relief with some of the characters. Throughout the film it is how the clever, white working class people of this hard working town have to overcome the maniacal working environment these Asian men have. Common stereotypes of the Asian man lay throughout the entire course of the movie, stereotypes that have been portrayed by the film industry of Asian men since its inception. The main stereotype in this movie is that Asian men only care about their jobs and their careers and little else. That the Asian man will go through great sacrifice to get to the top of the business that they work for. From beginning to end, many white families are portrayed in the movie showing that the American people have family values. Yet absent through the whole course of the picture is any Asian man with his family. This signifies that the Asian group does not have time, nor wants to make time to have a family life because they are trying to succeed in business. The Asian boss in the film wanted the results to his li... ...en in this film have any strong masculine qualities. They cannot take charge, they are easily intimidated, and they are never assertive with their beliefs and restrictions giving the impression to the movie viewers that Asian Americans are docile beings and Asian Americans are obstacles easily overcame. Overall, the object of this movie is to entertain the audience sitting at home watching it, laughing at the mishaps and situations that happen along the way. The question is, however, at who’s expense does the laughter come? Perpetuating this stereotype only goes to further damage the way Asian Americans are seen by the American public. Also during the time the movie was being made, the yen and the dollar were in competition over which had more value. This movie in a subtle way suggests that American workers can overcome any adversity, while the Asian cast is lucky to have such determined Americans to help them out of their problems. The movie serves to inspire Americans by relying on a stereotype of Asians to show that Asian are weak and Americans are strong, and that they can overcome any challenge they rally behind.

Consider Thomas Hardy’s Essay

In the dictionary the word Isolation means to be separate or a part from others. I think if someone is isolated then it would be a negative aspect because they are alone and have nothing to do with anyone else. The reason for the various isolations in the two texts differs because of the different time periods they were set in. In the two books I am comparing is the â€Å"Withered Arm† by Thomas Hardy and â€Å"Of Mice and Men† by John Steinbeck. I feel that in both texts there are a few characters with their lives or they had illegitimate children. The text â€Å"Of mice and Men† was written in the 1930’s the time period of the depression. In the most of John Steinbeck’s books he describes the life of people working on the land and that his characters are all often poor. This was because he wanted to show how real the life was during that time. Within his books men and women rarely understood each other because of the lack of communication. During the time when John Steinbeck wrote â€Å"Of Mice and Men† people would frown upon coloured people, the handicapped, the old and women. They also were prejudice about women. The text the â€Å"Withered Arm† was written in the late 19th century in England. The book is set in a place called Wessex and the expectations at the time are different compared to the ones we have in today’s society. In that time social classes were expected to marry inside their class and not below that. Otherwise this would be considered a disgrace to the family of the higher class. Thomas Hardy introduces Rhode as his First character who is isolated. He establishes her isolation as her sitting on her away from the others â€Å"Where a thin fading women of thirty milked somewhat apart from the rest. † The word fading and somewhat apart from the rest reveals that she was separated from the rest of the milkmaids. Further on in the first chapter Hardy also establishes her loneliness by where she lives â€Å"†¦ lay part from that of the others, to a lonely spot high above the water-meads†¦ † this also show her isolation. The characters who are lonely are Candy, Crooks and Curley’s wife in the text â€Å"Of Mice and Men. † They are lonely because each one of them is different from everyone else. Such as Crooks is black, Candy is disabled and Curley’s wife is a women. The reason for them being lonely is because of the society’s attitude, which they lived in. The two characters that are not lonely are George and Lennie. This is as they have each other for company whereas everybody does not. Lennie and George treat each other, as they were family because they have been together for a very long time. â€Å"Because I got you an’___ An’ I got you. We got each other, that’s what, that gives a hot in hell about us’. † That quote indicates what Lennie say to George about them having each other to look after and keeping each other company. George needed Lennie because he wanted someone who would listen to him and not say anything. Lennie need George’s because he is not able to handle himself and also George promised Lennie’s aunt that he would look after him. Thomas Hardy describes Rhodes Brooks house as it old and worn † It was built of mud walls, the surface of which had been washed by many rains†¦ left none of the original flat face visible†¦ here and there in the thatch above a rafter showed like a bone protruding through the skin. † This suggests that Rhode did not a great house and that it was old just like her. The quote also indicates that the house had been through some hard times. In the text â€Å"Of Mice and Men† John Steinbeck writes about one female character that is known as Curley’s wife. As the reader I feel sympathy for her, as she is the only woman on the ranch. She is also isolated because her husband does not like her talking to any of the other workers, and also her own husband hardly speaks to her. The author has not given her a name because during that time period women were not as important as men, furthermore she is so isolated that the author decided on not given her a name. The effect this has on the reader is that she belongs to Curley unlike her being an individual person. So therefore the reader feels a little bit of sympathy for her. Thomas Hardy writes about a little boy in his book † Withered Arm† who is also nameless like Curley’s Wife. In the book he is referred as Rhode’s son. Rhode’s son is isolated because his mother had an affair with Farmer Lodge. The main reason that he is isolated is that his mother moved further away from the farm, so therefore he does not live close by to anybody. I feel that Rhode’s son is a victim of the circumstances between Farmer Lodge and Rhode because he was a product of their affair, and then Rhode moved away so she could be away from society. As a result Rhode’s son does not have friends. John Steinbeck writes about another isolated man named Crooks. The reason Crooks is so isolated is because during the time period everyone was prejudice against coloured people, and he was black. Another reason he is isolated as that he isolates himself to have some respect in the white world. Crooks was born with a disability, therefore he feels that he need to isolate himself further. He makes friends with Candy and Lennie as they isolated on the farm. When Crooks first meets Candy and Lennie it says † †¦ he kept is his distance and demanded that other people keep theirs. † This indicates that Crooks does not want anyone to be close to him. Though as the story goes on he makes friends with Candy and Lennie. I feel sorry for Crooks for being coloured and handicapped as he is very friendly person. In both the texts that I read there are two more handicapped people, named Gertrude from the † Withered Arm† and Candy from † Of Mice and Men†. Candy is isolated as he is old and has only got one arm since it was cut off when he was working on the farm. Gertrude isolated because one night Rhode cast a spell on her arm. In both texts Gertrude and Candy are alike because of their arms. They are not as isolated as Crooks or Rhode, since they only have a small isolation problem, unlike the rest. In the beginning of the text † Withered Arm† Farmer Lodge is presented as being bold and proud. He is proud as he has a new wife Gertrude, who is a lot younger than him and plus she is very beautiful. Gertrude starts to get a problem in one of her arms, as time passes her arm gets worse, therefore Farmer Lodge feels as she is not as pretty as before. This makes Farmer Lodge change. He also feels depressed since his son is hung and this changes him. The reason for him to isolate himself is that all these problems are occurring around him and he feels that it is his fault. So he moves away from his farm. In conclusion I consider that isolation is a negative aspect in someone’s life. I think that when people are isolated dreaming keeps them from getting trough. Like for instance Lennie and George’s dream to open up a farm or their own and Rhode’s dream to get back with Farmer Lodge. Show preview only The above preview is unformatted text This student written piece of work is one of many that can be found in our GCSE John Steinbeck section.

The Dietary Guidelines For Nutrition And Human Needs

According to the History of the Dietary Guidelines for Americans , In 1977 after years of scientific review and controversy the US Senate Select Committee on Nutrition and Human Needs, led by Senator George McGovern, recommended Dietary Goals for the American people (US Senate Select Committee, 1977). The Goals included complementary nutrient-based and food-based recommendations. The first goal aim attention at energy balance and urged that, to prevent overweight, Americans should endure only as much energy as they are necessary. Overweight Americans should consume less energy and expend more energy. For the nutrient-based Goals, the Senate Committee recommended Americans, boost their consumption of complex carbohydrates and â€Å"naturally occurring sugars;† and make less consumption of refined and processed sugars, total fat, saturated fat, cholesterol, and sodium (1).) The beginning of the Dietary Goals encounter debates and controversy, as industry groups and the scientifi c community expressed questioning that the science available at the time supported the specificity of the numbers provided in the Dietary Goals. To support the credibility of the science used by the Committee, the US Department of Agriculture and US Department of Health and Human Services (then called the Department of Health, Education, and Welfare) scientists from the two Departments acquire additional expertise from the scientific community throughout the country to address the public’s need forShow MoreRelatedDietary Guidelines For Health And Chronic Disease Essay1521 Words   |  7 Pagesthe US government uses dietary guidelines for Americans and how the guidelines were supposed to help by creating a healthy eating pattern to maintain health and reduce the risk of chronic disease. . Diet and chronic diseases are sometimes connected. 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